brca1 gene การใช้

• That could occur even if the BRCA1 gene is perfectly normal.
• The test will tell women which type of BRCA1 gene they have.
• The BRCA1 gene, he noted, has a very different role.
• What's still unclear is what role the mutated BRCA1 gene plays.
• The BRCA1 gene in those cells appeared normal.
• Pregnancy appears to induce the BRCA1 gene to produce the cancer-suppressing protein.
• The scientists also demonstrated the therapeutic possibilities of the BRCA1 gene in animal experiments.
• In contrast, a single copy of a mutated BRCA1 gene confers a cancer risk.
• An interesting possibility raised by the researchers involved the BRCA1 gene's link with pregnancy.
• About 1 in 200 women in the United States are thought to carry a mutant BRCA1 gene.
• He asked whether he could cure tumors in animal experiments by restoring a normal BRCA1 gene to cells.
• At first, researchers hoped to develop a simple test for the mutation that inactivated the guardian BRCA1 gene.
• They supplied the women with normal BRCA1 genes, injecting the women in their abdomens with viruses containing the genes.
• If the BRCA1 gene is damaged by mutation, the p21 gene never gets the message to do its job.
• Holt said in an interview that previous studies have shown that the peak activity of the BRCA1 gene occurs during pregnancy.
• But when Jensen treated the mice with the BRCA1 gene, the tumors began to shrink and a few melted away.
• The viruses, which can slip through cell walls, were necessary to carry the BRCA1 genes inside the tumor cells.
• Other mice that received mutant BRCA1 genes _ and thus no protein _ showed no such effect and died quickly of cancer.
• They found that the protein product of the BRCA1 gene is closely associated in cells with the product of a gene called Rad51.
• The BRCA1 gene mutation is thought to be a factor in only a small percentage of both breast and ovarian cancer cases nationally.